The Mighty NAT Agency began as a new incarnation of the Mighty Agency from Science Guinea Pigs: Mighty Agency , also undergoing the name, "The Rescue Allies Space-Time Gang". It combined natural gifts, mutant abilities, and cybernetics into an all powerful team that saves the world. One time, their goal was changed to time-traveling in order to save Bring, L.E.O., and D'Samuel's brothers, A. Dumbhead and Catch, from going blind and getting possessed, as well as Veriol's bud, Zak, from going insane. They were last led by Veriol Boxley. Duncan Vadenport has also led them in the past. Their final headquarters was the Vadenport Robotics School .
- Catch Vadenport -Former ally\brains\martial artist
- D'Samuel Vadenport -Former ally\substitute martial artist
- Duncan Vadenport -Former Brains\Mission Leader
- Veriol Boxley- The Brains\ Mission Leader
- Bring Vadenport - The Speed\Agility
- Zak Bobbins- The Ranger\ Heart
- Rylie Rain - The Martial Artist\ The Muscle
- Dyna Fields - The Voice
- W.E.I.R. Dellow - Co-Mission Leader\ The Brains 2
- Sugna Hazelnut - Mission Specialist
- Erfletch Boxley - The Hands\Timekeeper
- L.E.O. Ooley -Current Ally\Substitute
- Duncan Vadenport- Adult Aide, Mentor, Backup, and Co-Mission Specialist.