Annie, an aspiring musician, met Douglas in 1988 at a Science-Music Mixer Dance. They fell in love and were married in 1990. Unfortunately, in 1991, Annie was diagnosed with Parkinson's Disease. She also found that she could not have children. Annie begged Douglas to take her DNA to somehow keep her memory alive, which Douglas did. Annie and Douglas briefly separated in 1996 after Annie found out that Douglas has used her DNA in engineering a bionic super-human named Adam. However, she was then rather forgiving when the doctors told her she had 5 years to live, so she needed to be with her family as much as possible. Annie's stuttering and bad walking posture eventually led to her becoming bed-ridden in 1999. That was the year that Donald took Douglas and Annie's kids, Adam, Bree, and Chase. By 2001, Douglas couldn't handle her misery. They quickly divorced, and Douglas remarried Katy Clutterbucket. However, Kermit Hart stole Katy and Evelyn, leaving Douglas to go to his best friend, Amanda Ripley. Douglas divorced Amanda after having Heather, and returned to Annie on her deathbed. Annie begged for one more son, by the name of Daniel. Douglas took a piece of her DNA and created Daniel as a result. Douglas buried her in a secret compartment of Donald's lab, with the engraving "Annie Henderson Davenport March 1962- July 2002". She was 40 years old.